Clinical Trials

🔬 Top Active Tinnitus Clinical Trials

Live data from ClinicalTrials.gov — Stars indicate evidence strength (phase + enrollment size)

Trial Phase Enrolled Est. End Evidence Intervention
Venous Stenting Evaluation in Patients With Intracrania N/A 114 2030-01-05 ★★☆☆☆ Acetazolamide, Stent (Tentos 4F or Precise Pr
Navigated Repetitive TMS for Chronic Tinnitus N/A 50 2027-10-30 ★★☆☆☆ navigated rTMS
TNF-α Treatment of Blast-Induced Tinnitus Phase 2 88 2026-09 ★★★★☆ Etanercept, Saline
WHITBY: Working Towards Better Healthcare Interventions N/A 40 2026-09 ★☆☆☆☆ transcranial Direct Current Stimulation
Bimodal Electrical-Sound Stimulation and Auditory Train N/A 100 2029-01-30 ★★☆☆☆ Real NITESGON, Sham NITESGON
Noninvasive Therapy for Tinnitus N/A 40 2027-05-31 ★☆☆☆☆ Cold pack-delivered mild therapeutic hypother
SPI-1005 for the Treatment of Meniere’s Disease (Open L Phase 3 200 2026-12 ★★★★★ Ebselen
An fMRI Investigation of the Effects of IV Lidocaine on EARLY/Phase 1 40 2027-12-31 ★☆☆☆☆ IV Lidocaine
Evaluating How a Tinnitus Implant Affects Tinnitus Loud N/A 16 2026-04 ★☆☆☆☆ Tinnitus Implant System
Tinnitus Patient Preferences Survey N/A 500 2025-12-30 ★★★☆☆ Survey using a questionnaire.

★★★★★ = Phase 3 + large enrollment | ★★★ = Phase 2 | ★★ = Early phase | Source: ClinicalTrials.gov

Active Tinnitus Clinical Trials

Live data from ClinicalTrials.gov. These are currently recruiting or active studies related to tinnitus.

Phase 1
Phase 2
Phase 3 / Recruiting
Active, not recruiting
Last updated: March 14, 2026 · 30 active trials
Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide
N/A
Recruiting
Enrollment: 114
Est. completion: 2030-01-05
Acetazolamide, Stent (Tentos 4F or Precise ProRX)
NCT06945848 View on ClinicalTrials.gov →
Navigated Repetitive TMS for Chronic Tinnitus
N/A
Recruiting
Enrollment: 50
Est. completion: 2027-10-30
navigated rTMS
NCT07435298 View on ClinicalTrials.gov →
TNF-α Treatment of Blast-Induced Tinnitus
Phase 2
Recruiting
Enrollment: 88
Est. completion: 2026-09
Etanercept, Saline
NCT04066348 View on ClinicalTrials.gov →
WHITBY: Working Towards Better Healthcare Interventions for Tinnitus: a Brain Stimulation studY
N/A
Recruiting
Enrollment: 40
Est. completion: 2026-09
transcranial Direct Current Stimulation
NCT06628414 View on ClinicalTrials.gov →
Bimodal Electrical-Sound Stimulation and Auditory Training for Chronic Tonal Tinnitus
N/A
Recruiting
Enrollment: 100
Est. completion: 2029-01-30
Real NITESGON, Sham NITESGON, Active Listening
NCT07393880 View on ClinicalTrials.gov →
Noninvasive Therapy for Tinnitus
N/A
Recruiting
Enrollment: 40
Est. completion: 2027-05-31
Cold pack-delivered mild therapeutic hypothermia, Sham device
NCT07071480 View on ClinicalTrials.gov →
Amplification and Tinnitus Masker Performance and Benefit for Adults With Hearing Loss and Tinnitus
N/A
Enrolling By Invitation
Enrollment: 100
Est. completion: 2027-12
Hearing Aid, Tinnitus Masker
NCT07298499 View on ClinicalTrials.gov →
Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)
N/A
Recruiting
Enrollment: 56
Est. completion: 2028-09-18
The intervention is an audio-proprio-phonatory training, high-density electroencephalogram (HD-EEG)
NCT06880367 View on ClinicalTrials.gov →
SPI-1005 for the Treatment of Meniere’s Disease (Open Label)
Phase 3
Recruiting
Enrollment: 200
Est. completion: 2026-12
Ebselen
NCT06859788 View on ClinicalTrials.gov →
Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere’s Disease
N/A
Recruiting
Enrollment: 33
Est. completion: 2026-05-05
Vestibular Rehabilitation + Cervical Mobilization, vestibular rehabilitation
NCT07272473 View on ClinicalTrials.gov →
Efficacy Analysis of Personalized-Target Transcranial Magnetic Stimulation (TMS) in the Treatment of Chronic Tinnitus: A Single-Center, Single-Blind Randomized Clinical Trial
N/A
Recruiting
Enrollment: 116
Est. completion: 2030-08
continuous theta burst stimulation
NCT07267455 View on ClinicalTrials.gov →
An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus
EARLY_Phase 1
Recruiting
Enrollment: 40
Est. completion: 2027-12-31
IV Lidocaine
NCT04192773 View on ClinicalTrials.gov →
Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss
N/A
Recruiting
Enrollment: 16
Est. completion: 2026-04
Tinnitus Implant System
NCT06641999 View on ClinicalTrials.gov →
Investigating EEG as a Biomarker for Tinnitus Improvement After Bimodal Stimulation
N/A
Recruiting
Enrollment: 24
Est. completion: 2026-06-30
Lenire Device
NCT07158034 View on ClinicalTrials.gov →
Management of Acute Tinnitus With Migraine Medications
Phase 4
Active Not Recruiting
Enrollment: 100
Est. completion: 2026-12
Nortriptyline, Topiramate, Paroxetine
NCT06799169 View on ClinicalTrials.gov →
Notched Noise Therapy for Suppression of Tinnitus
N/A
Recruiting
Enrollment: 108
Est. completion: 2026-05-31
Hearing Aid and Notched Noise Therapy, Hearing Aid and Broadband Noise, Hearing Aid
NCT04661995 View on ClinicalTrials.gov →
Assessment of Customized Bimodal Stimulation for Tinnitus
N/A
Active Not Recruiting
Enrollment: 20
Est. completion: 2026-07
Bimodal Neuromodulation
NCT07092033 View on ClinicalTrials.gov →
Treatment of Temporomandibular Joint Disorders With a Stabilizing Occlusal Splint in Somatosensory Tinnitus
N/A
Recruiting
Enrollment: 63
Est. completion: 2026-06-30
Stabilizing occlusal splint, placebo splint
NCT07211711 View on ClinicalTrials.gov →
Intracranial Venous Stenting Evaluation in Patients With Idiopathic Intracranial Hypertension in the Early Phase
N/A
Recruiting
Enrollment: 114
Est. completion: 2029-04-30
Best medical care, Intervention (stenting)
NCT06919744 View on ClinicalTrials.gov →
Internet-Based Mindfulness-Based Cognitive Therapy (iMBCT) for Chronic Tinnitus Patients
N/A
Recruiting
Enrollment: 78
Est. completion: 2026-06-19
Mindfulness-Based Cognitive Therapy (Internet-delivered), No intervention
NCT07183826 View on ClinicalTrials.gov →
Interventional Treatment of Chronic Tinnitus With Acoustic Stimulation
N/A
Recruiting
Enrollment: 200
Est. completion: 2027-10-01
Acoustic Stimulation
NCT07185061 View on ClinicalTrials.gov →
Daily Bitemporal Low-frequency Transcranial Random Noise Stimulation in Tinnitus (tRNS2-tin)
N/A
Recruiting
Enrollment: 30
Est. completion: 2025-12-31
lf-tRNS
NCT02615600 View on ClinicalTrials.gov →
External Therapy for Tinnitus Management
N/A
Recruiting
Enrollment: 80
Est. completion: 2026-12-01
Cold pack-delivered mild therapeutic hypothermia, Sham (No Treatment)
NCT07017998 View on ClinicalTrials.gov →
Somatosensory Tinnitus RCT
N/A
Recruiting
Enrollment: 72
Est. completion: 2027-09-30
Physical Therapy, Sound-based Therapy, Combination Therapy
NCT05434637 View on ClinicalTrials.gov →
Assessment of a Novel Sound-based Treatment for Managing Distress Related to Tinnitus
N/A
Recruiting
Enrollment: 50
Est. completion: 2026-11-01
White Noise, Music and Auditory Beat Stimulation
NCT06083519 View on ClinicalTrials.gov →
tVNS and Myofascial Release in Tinnitus
N/A
Active Not Recruiting
Enrollment: 45
Est. completion: 2025-10-10
Transcutaneous Vagus Nerve Stimulation, Myofascial Release Exercises, Standard medical treatment
NCT07155733 View on ClinicalTrials.gov →
Efficacy of Donepezil in Patients With Chronic Tinnitus
Phase 4
Active Not Recruiting
Enrollment: 70
Est. completion: 2025-12-09
Donepezil group, Placebo group
NCT07153991 View on ClinicalTrials.gov →
SiREX-Stent for the Treatment of SymptOmatic Lateral VEnous Sinus Stenosis
N/A
Recruiting
Enrollment: 78
Est. completion: 2029-01
Sinus Stenting
NCT06726928 View on ClinicalTrials.gov →
Treatment for PTSD and Tinnitus
N/A
Recruiting
Enrollment: 160
Est. completion: 2028-08
Cognitive Processing Therapy, CBT-t
NCT07106593 View on ClinicalTrials.gov →
Low-intensity TUS for Sleep Disturbances in Patients With Chronic Tinnitus
N/A
Recruiting
Enrollment: 14
Est. completion: 2026-06-30
Low-intensity transcranial ultrasound stimulation
NCT06776705 View on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov. This page is for informational purposes only. Always consult your healthcare provider.