Pirfenidone Reduces Cochlear Implant Scarring
**A local application of the anti-fibrotic drug pirfenidone at the time of cochlear implant surgery reduced tissue scarring around the electrode by 40% in guinea pigs.** This reduction in fibrosis, a known barrier to optimal hearing outcomes, was comparable to the effect achieved by the steroid dexamethasone and occurred without signs of ototoxicity. The findings,…
