Cognitive impairment is a frequent and debilitating feature of post-COVID-19 syndrome (PCS), with no established treatments targeting its underlying causes. A new clinical trial, the EGb COCOS study, will test whether a specific Ginkgo (Ginkgo biloba extract) biloba extract can address the neurobiological mechanisms driving this cognitive dysfunction. Key Takeaways No current treatments directly address…
🔬 Active Clinical Trial: NCT07655440 | Status: NOT_YET_RECRUITING | Phase: PHASE4 View full trial details on ClinicalTrials.gov → New Trial Tests Migra…
Key Takeaways The DTI-ALPS index, once thought to measure the brain’s glymphatic “clean-up” system directly, is now understood to be a more complex composite biomarker. Its value is heavily influenced by the brain’s white matter structure, including fiber orientation and the geometry of tissue surrounding blood vessels. Changes in the ALPS index may reflect a…
The widely used neuroimaging method known as DTI-ALPS, designed to assess the brain’s waste clearance system, may not measure what scientists originally thought. Researchers from Nagoya University propose a fundamental reinterpretation of the technique, arguing it serves better as a general biomarker of brain tissue health than a direct gauge of glymphatic function. Key Takeaways…
Key Takeaways Young adults with tinnitus and normal hearing showed enhanced auditory brainstem responses and better vowel discrimination than peers without tinnitus. Middle-aged adults with tinnitus had no neural enhancements and performed worse on speech-in-noise tests compared to controls. Tinnitus shifted the brain’s reliance from peripheral to central auditory processing, a pattern not seen in…
A novel sound therapy that embeds specific therapeutic tones within music led to greater reductions in tinnitus-related distress than a control treatment over three months. The pilot study from the Otolaryngology Department at Hospital Clínico Universidad de Chile suggests this modified Music-Integrated Desynchronization Sound Therapy (mMIDST) could offer a more practical and tolerable approach to…
A significant portion of people with tinnitus have clinically normal hearing, challenging the assumption that hearing loss is always the root cause. A new study published in *[Journal Name]* provides evidence that the auditory profile of a person with tinnitus changes dramatically with age, revealing distinct patterns of neural enhancement in youth and degraded processing…
A 55-year-old woman with no known immune system issues presented to an emergency department with worsening dizziness and new, sudden hearing loss in both ears. After a comprehensive investigation, doctors identified an unexpected cause: neuroinvasive West Nile virus (WNV). Her case, documented in a 2025 report in Laryngoscope Investigative Otolaryngology, is a rare but important…
Key Takeaways Cochlear implants significantly improved speech understanding in quiet and noisy environments for adults with single-sided deafness. Patients experienced measurable improvements in binaural hearing, including the head shadow and binaural squelch effects. Tinnitus reduction, less listening fatigue, and improved quality of life were common patient-reported benefits. The study provides strong post-market evidence supporting cochlear…
Key Takeaways Tinnitus and hearing loss are common after blast injuries, acoustic trauma, and head injuries, but recovery patterns differ by the type of trauma. Early treatment, ideally within days to two weeks of injury, is strongly linked to better recovery outcomes. Traumatic brain injury can cause central auditory processing problems even when a standard…
A new study has validated the first questionnaire for assessing misophonia in Marathi, a language spoken by over 83 million people in India. The research, conducted by audiologists Suman Chalotra, Nirali Chauhan, and Deepa Valame, found that 11% of participants showed moderate to severe symptoms of the condition, with a significantly higher prevalence among women….
Key Takeaways Tinnitus is not a single condition; it presents with distinct auditory profiles in young versus middle-aged adults with normal hearing. Young adults with tinnitus showed enhanced neural responses and better vowel discrimination compared to peers without tinnitus. Middle-aged adults with tinnitus displayed degraded neural encoding and poorer speech-in-noise performance than their matched controls….
